Toxicological analyses of the venoms of Nigerian vipers Echis ocellatus and Bitis arietans

Table 3 Edematogenic activity of crude venom and venom proteins of B. arietans

Time (Min)	Crude venom		SVMP fraction		SVSP fraction		PLA₂ fraction
Time (Min)	Envenomed foot (mm)	Control	Envenomed foot (mm)	Control	Envenomed foot (mm)	Control	Envenomed foot (mm)	Control
0	1.12 ± 0.00^a	1.13 ± 0.00^a	1.81 ± 0.01^a	1.72 ± 0.01^a	2.11 ± 0.01^a	2.10 ± 0.01^a	1.70 ± 0.00^a	1.71 ± 0.01^a
30	3.24 ± 0.01^b	1.12 ± 0.00^a	3.51 ± 0.00^d	1.72 ± 0.00^a	3.60 ± 0.00^c	2.09 ± 0.02^a	4.04 ± 0.00^d	1.72 ± 0.01^a
60	4.42 ± 0.01^d	1.13 ± 0.00^a	3.93 ± 0.02^f	1.73 ± 0.01^a	3.74 ± 0.00^d	2.10 ± 0.01^a	4.65 ± 0.00^e	1.72 ± 0.02^a
120	3.61 ± 0.00^c	1.13 ± 0.00^a	4.57 ± 0.00^g	1.73 ± 0.02^a	5.47 ± 0.00^g	2.08 ± 0.01^a	5.60 ± 0.00^g	1.72 ± 0.01^a
180	×	×	3.72 ± 0.00^e	1.73 ± 0.00^a	3.85 ± 0.00^e	2.07 ± 0.02^a	4.84 ± 0.00^f	1.71 ± 0.00^a
240	×	×	2.48 ± 0.00^b	1.73 ± 0.01^a	2.82 ± 0.00^b	2.08 ± 0.00^a	3.34 ± 0.00^c	1.73 ± 0.01^a
300	×	×	2.52 ± 0.00^c	1.73 ± 0.01^a	4.13 ± 0.00^f	2.07 ± 0.01^a	3.11 ± 0.00^b	1.71 ± 0.00^a

Data are mean ± SD from three determinations. Data with different superscripts in a column are significantly different at p < 0.05. × indicates mortality

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