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Table 1 Clinico-epidemiological characteristics of SARI patients during the pre- and COVID-19 pandemic periods

From: Characterizing deaths among adult patients with severe acute respiratory infection: during the pre- and COVID-19 pandemic periods in Bangladesh, 2018–2022

 

Patient enrollment

Total

N = 8216

Pre-COVID-19 pandemic, N = 4392

During COVID-19 pandemic, N = 3824

n (%)

n (%)

n (%)

Demographic characteristics

   

 Age

   

  18–30 years

1688 (20.55)

1153 (26.25)

535 (13.99)

  31–40 years

1133 (13.79)

565 (12.86)

568 (14.85)

  41–50 years

1228 (14.95)

579 (13.18)

649 (16.97)

  51–60 years

1486 (18.09)

731 (16.64)

755 (19.74)

    ≥ 60 years

2681 (32.63)

1364 (31.06)

1317 (34.44)

Median age (IQR), years

50 (32–60)

45 (28–60)

50 (35–60)

Male

5127 (62.40)

2783 (63)

2344 (61)

Clinical characteristics

   

 Runny nose

3186 (38.78)

1744 (39.71)

1442 (37.71)

 Headache

4597 (56)

2690 (61.25)

1907 (49.87)

 Sore throat

1736 (21.13)

993 (22.61)

743 (19.43)

 Difficulty breathing reported on admission

5542 (67.45)

2491 (56.72)

3051 (79.79)

 Body ache

4420 (53.80)

2474 (56.33)

1946 (50.89)

  ≥ 1 co-morbid condition (Self-reported)

3568 (43.43)

1760 (40)

1808 (47.28)

 Duration of symptoms prior to admission in days; median (IQR)

4 (3–6)

4 (2–5)

4 (3–6)

 Length of hospital stay in days; median (IQR)

3 (2–5)

3 (2–5)

3 (2–6)

Treatment received

   

 Antibiotic

6847 (83.34)

3257 (74.16)

3590 (93.88)

 Oxygen

3982 (48.54)

1248 (28.50)

2734 (71.51)

 Mechanical ventilation

23 (0.28)

17 (0.40)

6 (0.16)

 ICU support

28 (0.34)

19 (0.43)

9 (0.24)

Laboratory results

   

 SARS-CoV-2 detected

(n = 3816) $

1043 (27.33)

0 (0)

1043 (27.33)

 Influenza virus detected

1312 (16)

1010 (23)

294 (7.70)

Influenza virus types

 Influenza A

919 (70.05)

682 (67.52)

237 (78.48)

 Influenza B

393 (29.95)

328 (32.48)

65 (21.52)

 Influenza A and B

0 (0)

0 (0)

0 (0)

Subtypes of influenza A virus

 Influenza A(H1N1) pdm09

571 (43.52)

409 (40.50)

162 (53.64)

 Influenza A(H3N2)

339 (25.84)

264 (26.14)

75 (24.83)

 Influenza A(H5N1)

0 (0)

0 (0)

0 (0)

 Influenza A (inconclusive)Ȳ

9 (0.7)

9 (0.89)

1 (0.2)

Clinical outcome

   

 Death (total)

785 (9.55)

264 (6.01)

521 (13.62)

  1. $Testing of SARS-CoV-2 was initiated in March 2020
  2. ȲInconclusive: unable to characterize due to insufficient viral load in samples