Table 7 Predictors of adverse events following praziquantel treatment among pre-school children infected with S. mansoni
Variable | AEs after treatment | CRR (95%CI) | p value | ARR (95% CI) | p value | ||
|---|---|---|---|---|---|---|---|
AEs | No AEs | ||||||
Age groups (years) | 4 to < 6 years | 21 (22.3) | 73 (77.7) | 1.0 |  | – |  |
≥ 6 years | 33 (23.6) | 107 (76.4) | 1.1 (0.65,1.71) | 0.8 | – |  | |
Sex | Female | 18 (18.8) | 78 (81.3) | 1.0 | Â | 1.0 | Â |
Male | 36 (26.1) | 102 (73.9) | 1.4 (0.84, 2.30) | 0.2 | 1.2 (0.81, 1.73) | 0.4 | |
District | Chefe Kotijebesa | 1 (3.2) | 30 (96.8) | 1.0 | Â | 1.0 | Â |
Tullo | 49 (30.6) | 111 (69.4) | 9.5 (1.36, 66.18) | 0.02 | 8.8 (1.28, 60.93) | 0.03 | |
Finchawa | 4 (9.3) | 39 (90.7) | 2.9 (0.34, 24.55) | 0.3 | 4.4 (0.54, 35.31) | 0.2 | |
Infection status | S. mansoni only infected | 35 (21.3) | 129 (78.7) | 1.0 | Â | 1.0 | Â |
S. mansoni + STH infected | 19 (27.1) | 51 (72.9) | 1.3 (0 .78, 2.06) | 0.3 | – |  | |
Baseline infection intensity | Light | 12 (9.0) | 122 (91.0) | 1.0 | Â | Â | Â |
Moderate | 19 (28.8) | 47 (71.2) | 3.2 (1.66, 6.22) | 0.001 | 3.2 (1.69, 6.14) | < 0.001 | |
Heavy | 23 (67.7) | 11 (32.4) | 7.6 (4.20, 13.60) | < 0.001 | 6.5 (3.62, 11.52) | < 0.001 | |
Praziquantel dose | ≤ 1.5 tabs | 24 (22.6) | 82 (77.4) | 1.0 |  |  |  |
> 1.5 tabs | 30 (23.4) | 98 (76.6) | 1.0 (0.65, 1.66) | 0.9 | – |  | |