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Table 1 Description of 14 Core Laboratory Safety Elements taught at ACILT (2008–2014) in the Laboratory Biosafety and Infrastructure course

From: Measuring training effectiveness of laboratory biosafety program offered at African Center for Integrated Laboratory Training in 22 President’s Emergency Plan for AIDS Relief supported countries (2008–2014)

Core laboratory safety elements

Description

(1) Management’s Responsibilities*

Delegate, Resource, Implement, Enforce and Review

(2) Safety Business and Administration

Regulations, Policies, Committees, SOPs, Accreditations, IT-Systems, Communication-Public Relations

(3) Hazard/Risk Assessment Process

Review of Laboratories, Vivarium, and Areas that use/exposure to biological agents. (Hazard identification, Protection and Mitigation plans/processes)

(4) Occupational Health

Employee Medical Surveillance Program (Pre-exposure program, Emergency First-Aid training, Post-exposure protocol and Follow-up process.)

(5) Building/Facility and Maintenance

Building infrastructure, Safety-codes and systems (Mechanical/Ventilation, Electrical, Plumbing, Sewage, etc.)

(6) Safety Equipment and Maintenance

Personal Protective Equipment (PPE), Biosafety Cabinets, Small/Large-Safety equipment and instruments

(7) Chemical Management and Industrial Hygiene

Chemical safety program, use, accountability, and oversight (Cradle-to-grave responsibilities)

(8) Waste Management and Environmental Safety

Waste segregation, Labeling, Secure storage, Monitoring, Decontamination, Transport and Disposal methods (Safety oversight, responsibility accountability, and documentation)

(9) Emergency Preparedness and Response

Emergency Action Plan (Internal and External with local authorities), Communication Plan, Call-down Roster, and Drills

(10) Laboratory Biosecurity and High Hazard Disease Causing Agents

Delegation, Regulatory training, Proficiency, Implementation, Oversight and Documentation

(11) Transport of Biological Agents

Delegation, Regulatory training, Proficiency, Implementation, Oversight and Documentation

(12) Employee Training and Outreach

Hazard awareness, Protection mitigation processes, Practice demonstrations, Proficiency, Documentation

(13) Radiation Safety

Radiation compliance and permits, Radioisotopes, Laser safety, etc.

(14) Off-site satellite field and Laboratory Activities

Safety review of off-site activities involving use or exposure to hazardous biological agents

  1. *Management must delegate oversight for each of the 14 core laboratory safety elements and ensure annual review. Laboratory Safety Officer (biosafety officer) must have a detailed understanding of how each of these 14 core laboratory safety elements and concepts support the safe operation of biological laboratories