Differential cardiomyocyte transcriptomic remodeling during in vitro Trypanosoma cruzi infection using laboratory strains provides implications on pathogenic host responses

Table 1 Summarization of the pathways enriched by the upregulated genes in all the T. cruzi-infection conditions

	Pathway name	Common	Exclusive to Colombian/Y strain
Upregulated WikiPathways	DNA replication		O
	One carbon metabolism		O
	Glutathione and one-carbon metabolism		O
	Nucleotide metabolism		O
	Mitochondrial gene expression		O
	Hypertrophy model	O
	Homologous recombination	O
	Apoptosis	O
	ErbB signaling pathway	O
	Selenium metabolism selenoproteins	O
	Amino acid metabolism	O
	Spinal cord injury	O
	MAPK signaling pathway	O
Upregulated biological process GO terms	Nucleic acid metabolic process		O
	Nucleobase-containing compound metabolic process		O
	Heterocycle metabolic process		O
	Cellular nitrogen compound metabolic process		O
	Cellular aromatic compound metabolic process		O
	Organic cyclic compound metabolic process		O
	Nitrogen compound metabolic process		O
	RNA metabolic process		O
	Gene expression		O
	Response to reactive oxygen species	O
	Response to ionizing radiation	O
	Response to oxidative stress	O
	Response to hydrogen peroxide	O
	Cellular response to stress	O
	Primary metabolic process	O
	Response to inorganic substance	O
	Regulation of metabolic process	O
	Regulation of intracellular protein kinase cascade	O

ISSN: 1349-4147