Fig. 6
Top differentially expressed genes of the cardiomyocyte upon Trypanosoma cruzi infection. Extensively A upregulated (fold-change > 5) and B downregulated (fold-change < 0.2) genes of the cardiomyocyte at 24-h post-infection are listed. Δ Gene expression, the fold-change or ratio between gene expression level of the infected cardiomyocytes and the non-infected negative control. Arrdc4 arrestin domain containing 4, Txnip thioredoxin interacting protein, Gdf15 growth differentiation factor 15, Atf3 activating transcription factor 3, Soat2 sterol o-acyltransferase 2, Dusp8 dual specificity phosphatase 8, Chac1 cation transport regulator 1, Gtpbp2 GTP binding protein 2, Capn5 Calpain 5, Dhcr24 24-dehydrocholesterol reductase, Lgals9 lectin galactose binding soluble 9, Acat2 acetyl-coenzyme A acetyltransferase 2, Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, Mvd mevalonate (diphospho) decarboxylase, Tpcn1 two pore channel 1, Medag mesenteric estrogen dependent adipogenesis, Sulf2 sulfatase 2, Fam64a family with sequence similarity 64 member A, Midn midnolin, Ldlr low density lipoprotein receptor, Acat3 acetyl-coenzyme A acetyltransferase 3, Triobp TRIO and F-actin binding protein