Fig. 3

Distribution of malaria parasites encoding different PfCRT haplotypes. This map displays single surveys that analyzed haplotype variations for alleles reported on PfCRT 72–76 codon-positions. At least nine different PfCRT 72–76 variations comprising mainly the wild-type CVMNK (i.e., C72–V73–M74–N75–K76) and the CVIET (i.e., C72–V73–M74I–N75E–K76T) haplotypes were recorded and are indicated by specific colors. Pie charts shown on the map represent proportions of isolates harboring each of the PfCRT 72–76 haplotypes in individual surveys. Unshaded areas are provinces, where the PfCRT 72–76 haplotypes was analyzed (i.e., Haut-Katanga: 3; Kinshasa:10; Kwilu: 13; Lualaba: 15; Maniema: 17; Nord-Kivu: 19; Nord-Ubangi: 20; Sud-Kivu: 22; Tshopo: 25; and Tshuapa: 26)