Fig. 1

Antiviral effect of remdesivir (A) 5-ALA (B) and 5ALA with SFC (C) against SARS-CoV-2 Omicron variant. Vero E6 cells were pretreated with remdesivir, ALA with and without SFC for 72 h and challenged with SARS-CoV-2. Infected cell supernatants at 48 h pi (MOI 0.02) were quantified by quantitative real time RT-PCR assay. The blue and red lines represent the CC₅₀ and IC₅₀, respectively; the blue squares represent cell viability (%) and the red circles represent SARS-CoV-2 infection inhibition (%). Data were collected from at least two independent experiments (in replicate) and shown data correspond to the mean ± SD