Table 2 Anti-Toxoplasma activity of KET and control groups in brain tissue in the post-treatment groups
Drug/dose, mg | CT (mean ± SD) | Parasite load | P value |
|---|---|---|---|
KET | |||
2 | 25.40 ± 0.51 | 31,369 | P < 0.001 |
3 | 25.81 ± 1.09 | 21,043 | P < 0.001 |
KET and PYR | |||
2 + 50 | 27.26 ± 0.52 | 13,299 | P < 0.001 |
3 + 50 | 26.59 ± 19.00 | 16,630 | P < 0.001 |
PYR (positive control) | |||
50 | 25.54 ± 0.54 | 31,099 | P < 0.001 |
PBS (negative control) | 20.27 ± 0.75 | 1,325,000 | – |