Table 2 Drug resistance mechanisms involved in ophthalmic bacterial infections
Resistance mechanism | Resistance gene | Bacterial sources | Plasmid/Transposon/Chromosome |
|---|---|---|---|
Chloramphenicol acetyltransferases | cat (I, II, B2, B3, B4, B5, B6, B7, B8, P, S) | Escherichia coli | Tn9 |
R429 (catI) | |||
pSa (catII) | |||
pNR79:Tn2424 (catB2) | |||
pHSH2 (catB3) | |||
Haemophilus influenzae | pR1234 | ||
pMR375 (catII) | |||
Serratia marcescens | R478 | ||
Proteus mirabilis | Chromosome | ||
Bacillus subtilis | pTZ12 | ||
Staphylococcus aureus | pKH7 | ||
pUB112 | |||
pC223 | |||
pSCS6 | |||
pSCS7 | |||
pC194 | |||
pMC524-MBM | |||
Streptococcus pyogenes | Chromosome (catS) | ||
Klebsiella pneumoniae | pEKP0787-1 (catB4) | ||
pKB42 (catB8) | |||
Enterococcus spp. | pRE25 | ||
pRUM | |||
Pseudomonas aeruginosa | pPAM-101 (catB6) | ||
Chromosome (catB7) | |||
Plasmid (catB8) | |||
Neisseria meningitidis | Chromosome (catP) | ||
Morganella morganii | Tn840 (catB5) | ||
Chloramphenicol exporters | cml (A1, A4 A5, A6, A7) | Escherichia coli | R751 (Tn2000) (cmlA5) |
R26 | |||
Pseudomonas aeruginosa | RPL11 (Tn1403) (cmlA1) | ||
pR1033:Tn1696 (cmlA1) | |||
Plasmid (cmlA6) | |||
Chromosome (cmlA7) | |||
Klebsiella pneumoniae | pILT-3 (cmlA1) | ||
pTK1 (cmlA4) |