Table 1 IC50 and CC50 values of 5-ALA and 5-ALA with SFC against SARS-CoV-2 Omicron variant
From: 5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro
SARS-CoV-2 variants* | Compound | IC50 (µM) | CC50 (µM) |
|---|---|---|---|
Wuhan | 5-ALA | 207 |  > 2000 |
|  | 5-ALA/SFC | 235/58.7 |  > 2000/ > 500 |
Alpha | 5-ALA | 104 |  > 2000 |
|  | 5-ALA/SFC | 173/43.2 |  > 2000/ > 500 |
Beta | 5-ALA | 1592 |  > 2000 |
|  | 5-ALA/SFC | 1311/327.7 |  > 2000/ > 500 |
Gamma | 5-ALA |  > 2000 |  > 2000 |
|  | 5-ALA/SFC | 1516/379 |  > 2000/ > 500 |
Delta | 5-ALA |  > 2000 |  > 2000 |
|  | 5-ALA/SFC | 397/99.2 |  > 2000/ > 500 |
Omicron | 5-ALA | 329 |  > 2000 |
|  | 5-ALA/SFC | 765/191 |  > 2000/ > 500 |