Table 1 Clinical profile, investigations, and outcomes
From: Hyperferritinemia in children hospitalized with scrub typhus
Parameter | N = 72 |
|---|---|
Age in months | 60 (36, 96) |
Boys, n (%) | 45 (62.5) |
Weight in kg | 16.0 (11.4, 20.75) |
Weight in Z score | − 1.37 (− 2.18, − 0.24) |
PRISM III | 8 (5, 12) |
Duration of illness in days | 7 (5, 10) |
Clinical features | |
Fever, n (%) | 72 (100) |
Edema, n (%) | 35 (48.6) |
Fast breathing, n (%) | 27 (37.5) |
Abdominal pain, n (%) | 25 (34.7) |
Bleeding manifestations, n (%) | 17 (23.6) |
Altered sensorium, n (%) | 16 (22.2) |
Seizures, n (%) | 16 (22.2) |
Headache, n (%) | 14 (19.4) |
Purpuric rash, n (%) | 8 (11.1) |
Oliguria, n (%) | 6 (8.3) |
Hepatomegaly, n (%) | 66 (91.7) |
Splenomegaly, n (%) | 43 (59.7) |
Eschar, n (%) | 14 (19.4) |
Investigations | |
Hemoglobin, g/dl | 8.7 (7.4, 10.2) |
Platelet count, cells/mm3 | 44,000 (18,000, 80,000) |
Total bilirubin, mg/dl | 0.8 (0.6, 1.9) |
Aspartate transaminase, U/L | 185 (94, 285) |
Alanine transaminase, U/L | 79 (49, 125) |
International normalized ratio | 1.2 (1.0, 1.5) |
Treatment | |
Doxycycline, n (%) | 65 (90.3) |
Azithromycin, n (%) | 7 (9.7) |
IvIg only, n (%) | 2 (2.8) |
IvIg with steroid, n (%) | 2 (2.8) |
Outcome | |
Survivors, n (%) | 60 (83.3) |
Length of PICU stay, days | 5 (4, 9) |
Length of hospital stay, days | 5 (3, 8) |