Table 3 Multivariable linear mixed model analyses of factors associated with CD4 changes overtime among HIV-infected children-initiated ART Amhara region public hospitals (2010–2016)
Covariate | Estimate | 95% CI | |
|---|---|---|---|
Constant | 2.494 | 2.328 | 2.660 |
Time | 0.008 | 0.007 | 0.009 |
BMI | 0.005 | − 0.003 | 0.012 |
Age | − 0.015 | − 0.021 | − 0.009 |
Hemoglobin | 0.013 | 0.004 | 0.022 |
BWHO stage | |||
Stage I | 0 | ||
Stage II | − 0.046 | − 0.091 | − 0.0003 |
Stage III | − 0.039 | − 0.089 | 0.011 |
Stage IV | − 0.053 | − 0.149 | 0.043 |
Opportunistic infection | |||
Yes | − 0.044 | − 0.0845 | − 0.0042 |
No | 0 | ||
Functional status | |||
Working | 0 | ||
Ambulatory | 0.004 | − 0.036 | 0.044 |
Bedridden | 0.008 | − 0.209 | 0.225 |
Disclosure | |||
Yes | − 0.087 | − 0.129 | 0.046 |
No | 0 | ||
Mothers ARV status | |||
Yes | 0.055 | − 0.019 | 0.128 |
No | 0 | ||
Regimen type | |||
d4T + 3TC + NVP | 0 | ||
d4T + 3TC + EFV | − 0.143 | − 0.217 | 0.068 |
AZT + 3TC + NVP | 0.022 | − 0.020 | 0.064 |
AZT + 3TC + EFV | 0.070 | − 0.017 | 0.123 |
TDF + 3TC + EFV | 0.170 | − 0.010 | 0.330 |
Others* | 0.157 | − 0.004 | 0.310 |