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Table 3 Multivariable linear mixed model analyses of factors associated with CD4 changes overtime among HIV-infected children-initiated ART Amhara region public hospitals (2010–2016)

From: Predictors of CD4 count changes over time among children who initiated highly active antiretroviral therapy in Ethiopia

CovariateEstimate95% CI
Constant2.4942.3282.660
Time0.0080.0070.009
BMI0.005− 0.0030.012
Age− 0.015− 0.021− 0.009
Hemoglobin0.0130.0040.022
BWHO stage
 Stage I0  
 Stage II− 0.046− 0.091− 0.0003
 Stage III− 0.039− 0.0890.011
 Stage IV− 0.053− 0.1490.043
Opportunistic infection
 Yes− 0.044− 0.0845− 0.0042
 No0  
Functional status
 Working0  
 Ambulatory0.004− 0.0360.044
 Bedridden0.008− 0.2090.225
Disclosure
 Yes− 0.087− 0.1290.046
 No0  
Mothers ARV status
 Yes0.055− 0.0190.128
 No0  
Regimen type
 d4T + 3TC + NVP0  
 d4T + 3TC + EFV− 0.143− 0.2170.068
 AZT + 3TC + NVP0.022− 0.0200.064
 AZT + 3TC + EFV0.070− 0.0170.123
 TDF + 3TC + EFV0.170− 0.0100.330
 Others*0.157− 0.0040.310
  1. *TDF + 3TC + EFV, AZT + 3TC + LPV/r, ABC + 3TC + LPV/r