Fig. 2

Changes in weight and food intake of PbA-infected mice. A comparison of the weight changes of PbA-C57BL/6, PbA-BALB/c, and uninfected control mice from baseline to dissection (%, mean ± SD). Food intakes in the control groups were 3.8 ± 0.2 g in uninfected C57BL/6 mice and 2.9 ± 0.3 g in uninfected BALB/c mice per day. a Weight changes in uninfected C57BL/6 mice and PbA-C57BL/6 mice with cerebral malaria or uncomplicated malaria until day 8 post infection. In addition to day 8, significant differences between control and PbA-C57BL/6 mice were also observed on day 6 (p = 0.0244, Student’s t test) and day 7 (p = 0.000576, Student’s t test). b Weight changes in uninfected BALB/c mice and PbA-BALB/c mice until day 15 post infection. In addition to days 13 and 15, significant differences between control and PbA-BALB/c mice were also observed on day 14 (p = 1.07 × 10⁻⁸, Student’s t test). c The food intake by PbA-C57BL/6 mice was decreased on day 6 (p = 0.000754, Mann–Whitney U test), on day 7 (p = 0.0000387, Mann–Whitney U test), and on day 8 (p = 0.00045, Mann–Whitney U test) compared to those in the control mice. d The food intake by PbA-BALB/c mice was decreased on day 12 (p = 0.0444, Mann–Whitney U test) to day 15 (p = 0.0444, Mann–Whitney U test) compared to that in the control mice. *p < 0.05