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Table 3 Body weight, RBC, and WBC levels in mice after pre- and post-infection stratified according to supplement administration

From: Anti-trypanosome effects of nutritional supplements and vitamin D3: in vitro and in vivo efficacy against Trypanosoma brucei brucei

Parameters   T. b. brucei infection (+) and treatment with
Infection-free No treatment Vitamin D3 Polyphenon-60 Suramin
Body weight (g) Pre-infectionb 20.0 ± 1.05 22.4 ± 1.32   22.2 ± 0.89  
Post-infectionc   21.6 ± 0.94 20.4 ± 1.46 18.6 ± 0.96 20.3 ± 0.56
RBC (×106/ml) Pre-infectionb 8.30 ± 0.62 8.45 ± 0.37   11.2 ± 0.22  
Post-infectionc   6.42 ± 0.94a 10.9 ± 0.11 8.10 ± 0.23 9.90 ± 0.97
WBC (×103/ml) Pre-infectionb 5.90 ± 0.11 4.40 ± 0.14   4.17 ± 0.56  
Post-infectionc   4.60 ± 0.15a 2.20 ± 0.44a 3.50 ± 0.16a 3.70 ± 0.56a
  1. aStatistically significant differences between the four groups and infection-free group are shown after analysis of variance (ANOVA). p value is less than 0.05 to the chosen significance level
  2. bPre-infection: on day 4 of polyphenon-60 treatment but not yet infected with T. b brucei GUTat 3.1 strain
  3. cPost-infection: 7 days after infection