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Table 2 24-h urinary catecholamine excretion on the 5th day of treatment and autonomic nervous system dysfunction (ANSD) after exclusion of patients developed ANSD before day 5 (n = 240)

From: Urinary catecholamine excretion, cardiovascular variability, and outcomes in tetanus

Catecholamines

Median [Q1, Q3]

Multivariate model

No ANSD, N = 214 (89%)

ANSD, N = 26 (11%)

OR1

95% CI1

p-value

Log10 (adrenaline (nmol/day))

2.18 [1.85, 2.50]

2.75 [2.50, 2.92]

8.86

2.44, 37.60

0.002

Log10 (noradrenaline (nmol/day))

2.71 [2.45, 3.06]

3.17 [2.98, 3.40]

11.43

2.90, 52.45

 < 0.001

  1. 1OR odds ratio per one unit increased on a log base 10 scale of the urinary catecholamine excretion measured (nmol/day), CI confidence Interval
  2. Multivariate analyses: adjusted for age, sex, intrathecal and intramuscular treatment interventions, total dose of medications (benzodiazepines, pipecuronium) during the first 5 days
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Tropical Medicine and Health

ISSN: 1349-4147

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