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Fig. 5 | Tropical Medicine and Health

Fig. 5

From: Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents

Fig. 5

Luminescence intensity at different timepoints in the mice model infected with 5 × 103 trypomastigotes and treated with coptisine chloride (COP) (30 mg/kg, 2 × i.p.); positive control is benznidazole (BNZ) (100 mg/kg, 1 × p.o.); negative control is the drug solvent. Bioluminescence imaging was obtained in an IVIS Lumina II system. Data are presented as mean and standard deviation in intensity of three experiments (*p < 0.05, **p < 0.01, ***p < 0.005 when compared with vehicle). In this experiment, we excluded mice with luminescence intensity less than 1 × 107 in pre-drug measurements (Day 3)

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