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Fig. 4 | Tropical Medicine and Health

Fig. 4

From: Whole-genome analysis of a Vibrio cholerae O1 biotype classical strain isolated in 1946 in Sasebo city, Nagasaki prefecture, from a returnee from the northeast part of China

Fig. 4

A Operon alignments associated with the CRISPR–Cas system carried by Man9 or O395 are shown. The system is classified as subtype I-E. B Spacer alignments of CRISPR–Cas in six V. cholerae biotype classical strains, including Man9, are shown. Spacers are represented as numbered rectangles. Arrays are oriented with respect to the leader sequence located at the left. Black rectangles represent unique spacers present in the strain indicated. Identical spacers shared with more than one strain are shown with gray rectangles and aligned vertically. Missing spacers are indicated as blank. Possible known targets are listed at the bottom of the figure. (L) leader sequence

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