Fig. 1

Circular representation of the two chromosomes of Vibrio cholerae O1 biotype classical strain Man9 is illustrated. The outermost circle and the 2nd circle indicate the positions of the putative protein-encoding genes in clockwise and counter-clockwise directions, respectively. The 3rd circle represents the GC content which shows the deviation from the average GC content of the entire sequence. The 4th circle represents the GC skew. Chr chromosome, Ori replication origin, VPI Vibrio pathogenic island