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Fig. 7 | Tropical Medicine and Health

Fig. 7

From: Vaccination with a Zika virus envelope domain III protein induces neutralizing antibodies and partial protection against Asian genotype in immunocompetent mice

Fig. 7

Clinical results in neonates against ZIKV and DENV challenge. Body weight changes and survival rates were observed. C57BL/6 mice (n = 5 per group) were immunized with Z_EDIII or PBS at 0, 14, and 42 dpi. Immunized females were mated with homozygous breeding pairs. The survival rate and body weight changes in neonatal mice (n = 5 per group) were observed. Two-day-old neonatal mice were inoculated with PBS (a, b), MR766 (c, d), PRVABC59 (e, f), or DENV-2 (g, h) strains. Data show the mean ± SD of five mice per group. Statistical analysis *p < 0.05, **p < 0.01, ***p < 0.001

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Tropical Medicine and Health

ISSN: 1349-4147

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