Table 1 Progression of biochemical parameters of organ injury over the 1st 3 days

Liver functions and biochemistries

 AST (5–40 U/L)

680 U/L

18,716 U/L

 ALT (7–55 U/L)

1100 U/L

7148 U/L

 Alkaline phosphatase (ALP) (44–147 U/L)

453 U/L

223 U/L

 Total bilirubin (< 1.2 mg/dL)

10.3 mg/dL

19.7 mg/dL

 Direct bilirubin (< 0.4 mg/dL)

4.7 mg/dL

5.0 mg/dL

 INR (< 1.1)

1.4

1.84

 APTT (21–35 s)

107 s

58.6 s

 Albumin (3.4–5.4 g/dL)

3.8 g/dL

2.0 g/dL

 Plasma ammonia (10–47 µmol/L)

100.1 µmol/L

Renal functions and biochemistries

 Serum creatinine (S/Cr) (0.74–1.35 mg/dL)

0.49 mg/dL

4.5 mg/dL

 Blood urea (6–24 mg/dL)

19.5 mg/dL

 Serum sodium (135–145 mEq/L)

136 mEq/L

137 mEq/L

 Serum potassium (3.5–5.0 mEq/L)

5.3 mEq/L

6.6 mEq/L

 Urine full report

Sugar + 4

Protein + 4

No cells, casts

 Urine protein creatinine ratio

U. protein − 166.8 mg/dL

U. Creatinine − 4.55 mg/dL

UPCR − 36.66

Rhabdomyolysis

 Creatine phosphokinase (CPK) (10–120 µg/)

30,545 µg/L (on 12th /10/ 2021)

43,992 µg/L

Haematological

 Haemoglobin (Hb) (13.8–17.2 g/dL)

18.3 g/dL

13.8 g/dL

 White Blood Cells (WBC) (4.5–11.0 × 10⁹/L)

13.9 × 10⁹/L

19.8 × 10⁹/L

 Platelets (Plt) (150–400 × 10⁹/L)

280 × 10⁹/L

32 × 10⁹/L

Lung functions

 Ventilatory mode

Volume control ventilation

Volume control ventilation

 FiO₂

1.0

0.45

 PaO₂ (75–100 mmHg)

62.2 mmHg

102 mmHg

 PaCO₂ (38–42 mmHg)

50.9 mmHg

31.9 mmHg

Cardiac functions

 High sensitive troponin I (< 0.004 ng/ml)

3.45 ng/ml

 Brain natriuretic peptide (BNP) (20 pg/ml)

1130 pg/ml

Other

 C-reactive protein (CRP) (< 6)

171

on (12th /10/2021)

77.5

 Lactate dehydrogenase (LDH) (140–280 U/L)

12,104 U/L

 Lactate (< 2.3 mmol/L)

7.6 mmol/L

8.1 mmol/L

 pH (7.35–7.45)

7.13

7.26

 Base excess (− 2 to − 2 mEq/L)

− 11.8 mEq/L

− 12.7 mEq/L