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Table 7 Biochemical parameters of adult female Wistar albino rats treated with a single dose (2000 mg/kg) of aqueous extracts from selected medicinal plant species for 14 days

From: Phytochemical screening, antimycobacterial activity and acute toxicity of crude extracts of selected medicinal plant species used locally in the treatment of tuberculosis in Uganda

Parameters

Plant species

Control

AH-SB

AC-SB

CM-L

WU-SB

ZL-RB

AST (U/L)

261.90 ± 49.97

264.20 ± 43.02

211.23 ± 17.84

271.23 ± 65.38

190.80 ± 9.62

307.25 ± 17.55

ALT (U/L)

62.77 ± 8.20

78.07 ± 2.92

72.70 ± 9.40

57.63 ± 3.79

62.27 ± 6.68

63.45 ± 5.75

ALP (U/L)

80.33 ± 2.03

90.67 ± 10.35

47.33 ± 10.68

90.00 ± 11.93

95.67 ± 6.49

113.00 ± 9.00

TP (g/L)

68.97 ± 2.39

65.73 ± 2.04

73.13 ± 1.65

65.40 ± 0.56

65.27 ± 2.97

69.80 ± 0.60

BILT (μmol/L)

1.40 ± 0.21

0.90 ± 0.12

0.87 ± 0.38

1.30 ± 0.26

1.10 ± 0.12

3.10 ± 0.40**

ALB (g/L)

36.07 ± 1.32

37.90 ± 2.23

46.33 ± 8.49

35.37 ± 0.67

37.53 ± 1.31

49.75 ± 1.75

CRE (μmol/L)

57.33 ± 8.21

39.33 ± 6.69

45.33 ± 4.84

43.00 ± 0.58

46.67 ± 3.71

47.50 ± 1.50

Urea (mmol/L)

7.37 ± 0.32

10.17 ± 0.52*

8.83 ± 0.55

8.73 ± 0.99

8.40 ± 0.26

9.85 ± 0.65

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, TP total proteins, BILT bilirubin total, ALB albumen, CRE creatinine. Values are presented as mean ± SEM of triplicates (n = 3). *p < 0.05; **p < 0.01 indicate significant changes in comparison with the control