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Table 6 Hematological parameters (Mean ± SEM) of adult female Wistar albino rats treated with a single dose (2000 mg/kg) of aqueous extracts from selected medicinal plants species after 14 days

From: Phytochemical screening, antimycobacterial activity and acute toxicity of crude extracts of selected medicinal plant species used locally in the treatment of tuberculosis in Uganda

Parameters

Plant species

Control

AH-SB

AC-SB

CM-L

WU-SB

ZL-RB

RBC (106/µL)

8.40 ± 0.12

8.54 ± 0.36

8.32 ± 0.24

8.64 ± 0.02

8.44 ± 0.18

9.06 ± 0.17

HGB (g/dL)

14.27 ± 0.45

14.80 ± 0.25

14.60 ± 0.40

15.13 ± 0.33

15.30 ± 0.29

14.55 ± 0.25

HCT (%)

53.10 ± 1.53

50.73 ± 1.24

50.53 ± 1.20

49.77 ± 0.90

50.93 ± 0.90

48.45 ± 0.95

MCV (fL)

63.20 ± 1.11

59.50 ± 1.22

60.80 ± 0.32

57.63 ± 0.90*

60.37 ± 1.16

53.45 ± 0.05***

MCH (pg)

16.97 ± 0.32

17.40 ± 0.45

17.57 ± 0.12

17.50 ± 0.35

18.13 ± 0.33

16.05 ± 0.05

MCHC (g/dL)

26.90 ± 0.21

29.17 ± 0.30***

28.90 ± 0.15**

30.40 ± 0.21***

30.03 ± 0.09***

30.05 ± 0.05***

PLT (103/µL)

568.33 ± 35.20

787.33 ± 29.00

887.00 ± 53.50

523.00 ± 220.37

565.67 ± 228.46

858.00 ± 88.00

WBC (103/µL)

4.59 ± 1.53

6.30 ± 0.89

6.36 ± 1.71

5.16 ± 1.12

3.16 ± 1.09

5.26 ± 2.46

LYMPH (%)

67.43 ± 1.82

70.20 ± 3.19

67.13 ± 6.75

83.50 ± 3.31

82.70 ± 1.97

56.75 ± 4.25

MONO (%)

3.40 ± 1.16

0.73 ± 0.15

0.63 ± 0.03

0.40 ± 0.15

0.23 ± 0.12

3.90 ± 2.10

NEUT (%)

24.03 ± 1.67

23.90 ± 2.65

27.33 ± 7.27

14.83 ± 3.48

15.60 ± 1.47

24.40 ± 6.00

  1. RBC red blood cells, HGB hemoglobin, HCT hematocrit, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, PLT platelet, WBC white blood cells, LYMPH lymphocyte count, MONO monocytes, NEUT neutrophils. Values are presented as mean ± SEM of triplicates (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001 indicate significant changes in comparison with the control
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Tropical Medicine and Health

ISSN: 1349-4147

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