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Table 3 Association between factors and a positive blood smear in day one

From: Artemether–lumefantrine and dihydroartemisinin–piperaquine treatment outcomes among children infected with uncomplicated Plasmodium falciparum malaria in Mwanza, Tanzania

Factor

 + blood smear in day 1

Univariate analysis

Multivariate analysis

RR (95% CI)

p value

RR (95% CI)

p value

Drug

     

 ALU

43.10%

Ref

   

 DHP

40.45%

0.94 (0.67–1.30)

0.704

  

Sex

     

 Female

46.67

Ref

   

 Male

37.00

0.79 (0.57–1.10)

0.166

  

Age

     

 ≤ 5 years

50.48

Ref

 

Ref

 

 > 5 years

33.00

0.65 (0.47–0.92)

0.014

0.71 (0.52–0.97)

0.034

RBG (mmol/L)

     

 < 5

39.00

Ref

   

 ≥ 5

41.05

1.05 (0.75–1.49)

0.770

  

Hb g/dL

     

 ≤ 10

44.62

Ref

   

 > 10

38.06

0.86 (0.60–1.21)

0.370

  

BMI (kg/m2)

     

 Normal

42.68

Ref

   

 Underweight

45.45

1.07 (0.54–2.09)

0.855

  

 Overweight

40.00

0.94 (0.53–1.65)

0.822

  

 Obese

30.00

0.70 (0.27–1.85)

0.474

  

Parasite density (parasite/µl)

     

 Min–3999

12.77

Ref

 

Ref

 

 4000–20,000

30.36

2.38 (1.02–5.55)

0.045

2.64 (1.12–6.21)

0.026

 20,001–Max

61.76

4.84 (2.25–10.39)

0.000

4.75 (2.20–10.25)

0.000

Temp. in °C

     

 < 37.0

26.32

Ref

 

Ref

 

 37.0–37.9

47.83

1.82 (1.01–3.27)

0.046

1.62 (0.95–2.78)

0.077

 ≥ 38.0

42.71

1.62 (0.91–2.90)

0.103

1.32 (0.05–0.24)

0.318