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Table 4 Association of severity of disease with demographic characteristics, comorbidity and initial presenting symptoms in COVID-19 patients

From: Initial presenting symptoms, comorbidities and severity of COVID-19 patients during the second wave of epidemic in Myanmar

Variables Severity of diseasea p value COR (95% CI) p value AOR b (95% CI)
Not severe n (%) Severe n (%)
Sex
 Male 89 (82.4) 19 (17.6)   1   
 Female 87 (76.3) 27 (23.7) 0.264 1.45 (0.75–2.80)   
Age
 < 60 years 150 (84.3) 28 (15.7)   1   1
 ≥ 60 years 26 (59.1) 18 (40.9)  < 0.001 3.71 (1.79–7.65) 0.026 2.88 (1.14–7.29)
Educationc
 Below university 111 (81.0) 26 (19.0)   1   
 University and graduate 65 (76.5) 20 (23.5) 0.417 1.31 (0.68–2.54)   
Occupation
 Employed 105 (80.8) 25 (19.2)   1   
 Unemployed 71 (77.2) 21 (22.8) 0.515 1.24 (0.65–2.39)   
BMId
 Underweight or normal weight 130 (89.0) 16 (11.0)   1   1
 Overweight or obesity 46 (60.5) 30 (39.5)  < 0.001 5.29 (2.65–10.60) 0.001 3.87 (1.80–8.33)
Smoking status
 No 163 (85.8) 27 (14.2)   1   1
 Yes 13 (40.6) 19 (59.4)  < 0.001 8.82 (3.91–19.93)  < 0.001 6.74 (2.72–16.75)
Alcohol drinking
 No 166 (81.0) 39 (19.0)   1   1
 Yes 10 (58.8) 7 (41.2) 0.037 2.98 (1.07–8.32) 0.430 1.68 (0.46–6.05)
Comorbidity
 No 116 (84.1) 22 (15.9)   1   1
 Yes 60 (71.4) 24 (28.6) 0.026 2.11 (1.09–4.07) 0.782 1.13 (0.48–2.61)
Initial presenting symptoms
 Asymptomatic 41 (100.0) 0 (0.0)     
 Symptomatic 135 (74.6) 46 (25.4)     
  1. aSeverity of disease was categorized as “not severe” (asymptomatic, mild and moderate) and “severe”
  2. bAll independent variables with p value < 0.05 in bivariable analysis were included in multivariable logistic regression model
  3. cEducation was categorized as “below university” (primary, middle and high school education level) and “university and graduate”
  4. dBMI was classified as “underweight or normal weight” and “overweight or obesity”