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Table 2 Associations with mortality among 367 non-HCW COVID-19 inpatients in San Lazaro Hospital, January to October 2020

From: Epidemiological and clinical characteristics of the first 500 confirmed COVID-19 inpatients in a tertiary infectious disease referral hospital in Manila, Philippines

Characteristics All cases (n = 367) Died (n = 60) Discharged (n = 307) P-value
Age (years)
 Mean (SD) 51 (18) 59 (20) 49 (17) < 0.001
 Median (IQR) 53 (38–64) 65 (41–75) 51 (37–62)  
Age group (years)
 0–10 years old 7 (1.9) 0 7 (100.0) < 0.001
 11–20 years old 9 (2.4) 2 (22.2) 7 (77.8)  
 21–40 years old 91 (24.8) 11 (12.1) 80 (87.9)  
 41–60 years old 137 (37.3) 14 (10.2) 123 (89.8)  
 61–80 years old 107 (29.2) 24 (22.4) 83 (77.6)  
 80+ years old 16 (4.4) 9 (56.2) 7 (43.8)  
Sex
 Female 158 (43.0) 17 (10.8) 141 (89.2) 0.015
 Male 209 (57.0) 43 (20.6) 166 (79.4)  
Nationality
 Filipino 365 (99.5) 59 (16.6) 306 (83.8) 0.197
 Chinese 2 (0.5) 1 (50.0) 1 (50.0)  
Exposure history
 International travel history within 14 days prior to admission 9 (2.5) 2 (22.2) 7 (77.8) 0.247
 Exposed to a confirmed case 11 (3.0) 0 11 (100.0)  
 Risk of exposure in workplace 9 (2.5) 0 9 (100.0)  
 No identified exposure 338 (92.0) 58 (17.2) 280 (82.8)  
Reported symptoms
 Fever 227 (61.8) 39 (17.2) 188 (82.8) 0.583
 Cough 301 (82.0) 53 (17.6) 248 (82.4) 0.200
 Colds 91 (84.8) 9 (9.9) 82 (90.1) 0.071
 Difficulty of breathing 167 (45.5) 48 (28.7) 119 (71.3) < 0.001
 Headache 18 (4.9) 2 (11.1) 16 (88.9) 0.749
 Malaise/fatigue 39 (10.6) 3 (7.7) 36 (92.3) 0.168
 Diarrhoea 29 (7.9) 1 (3.5) 28 (96.5) 0.050
 Anosmia 31 (8.4) 1 (3.2) 30 (96.7) 0.041
 Ageusia 27 (7.4) 1 (3.7) 26 (96.3) 0.065
 Loss of appetite 23 (6.3) 5 (21.7) 18 (78.3) 0.558
Co-morbidities
 Hypertension 140 (38.1) 22 (15.7) 118 (84.3) 0.796
 Diabetes 74 (20.2) 14 (18.9) 60 (81.1) 0.486
 Bronchial asthma 15 (4.1) 0 15 (100.0) 0.145
 HIV 6 (1.6) 4 (66.7) 2 (33.3) 0.008
 Cardiac disease 17 (4.6) 3 (17.6) 14 (82.3) 0.747
 Tuberculosis (any form) 37 (10.1) 10 (27.0) 27 (73.0) 0.097
 At least one underlying disease 205 (55.8) 36 (17.6) 169 (82.4) 0.480
Clinical status
 Asymptomatic 0 0 0 < 0.001
 Mild 73 (19.9) 1 (1.4) 71 (98.6)  
 Moderate 106 (28.9) 0 104 (98.1)  
 Severe 114 (31.1) 23 (20.2) 89 (77.4)  
 Critical 63 (17.2) 36 (48.7) 38 (51.3)  
Intubated 29 (7.9) 28 (96.5) 1 (3.5) < 0.001
Duration between the onset of symptoms and admission
 Mean (SD) 8 (15) 5 (33) 8 (7) 0.229
 Median (IQR) 7 (5–10) 6 (4–9) 7 (5–10)  
 0–14 days 322 (88.7) 53 (16.4) 269 (87.6) 0.047
 15–30 days 35 (9.6) 4 (11.4) 31 (88.6)  
 > 30 days 6 (1.7) 3 (50.0) 3 (50.0)  
Hospitalisation days
 Mean (SD) 12 (9) 7 (9) 13 (9) < 0.001
 Median (IQR) 10 (7–15) 5 (1–10) 11 (8–16)  
Other diagnoses
 Pneumonia 181 (49.3) 49 (27.1) 132 (72.9) <0.001
 Upper respiratory tract infection 15 (4.1) 0 15 (100.0) 0.080
 Acute gastroenteritis 10 (2.7) 0 10 (100.0) 0.378
 Acute respiratory distress syndrome 48 (13.1) 33 (68.7) 15 (31.2) <0.001
Ct-values distribution N = 227 N = 36 N = 191  
  11–20 3 (1.3) 1 (33.3) 2 (66.70) 0.178
  21–30 63 (27.7) 14 (22.2) 49 (77.8)  
  31–40 159 (70.0) 20 (12.6) 139 (87.4)  
  > 40 2 (0.9) 1 (50.0) 1 (50.0)