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Table 2 Tetanus risk factors for mechanical ventilation (n = 164)

From: Risk factors associated with mechanical ventilation, autonomic nervous dysfunction and physical outcome in Vietnamese adults with tetanus

Parameter

No MV (n = 90)

MV (n = 74)

OR for MV

95% CI

P value

Median [IQR], mean (±SD) or count (%)

Age (years)

46 [37–59]

52.5 [43–65]

1.027

1.01–1.05

0.01

Male sex

72 (80.0%)

60 (81.1%)

1.07

0.49–2.36

0.86

Any comorbidities

30 (33.3%)

34 (45.9%)

1.70

0.90–3.22

0.10

Deep wound

2 (2.2%)

2 (2.7%)

1.22

0.14–10.39

0.84

Incubation period (days) (n = 122)

10 [7–14]

8 [6–11]

0.99

0.952–1.04

0.78

Period of onset (h) (n = 141)

48 [24–72]

48 [24–48]

0.98

0.97–0.99

0.004

Time from first symptom to admission (days) (n = 162)

4 [3–6]

3 [2–4]

0.74

0.62–0.86

< 0.001

History of difficulty breathing

10 (11.1%)

19 (25.7%)

2.76

1.22–6.62

0.02

Clinical Features during first 24 h of admission

 Highest SBP (mmHg)

136 [120–150]

140 [130–147.5]

1.01

0.99–1.03

0.38

 Highest heart rate (bpm)

90 [82–99.5]

97 [88–111.5]

1.05

1.03–1.08

< 0.001

 Heart rate range (bpm)

12 [8–20]

16 [10–26]

1.05

1.02–1.08

0.001

 Highest temperature (°C)

37.4 [37.0–37.6]

37.5 [37.0––38.0]

2.35

1.36–4.28

0.003

SpO2 (%)

97 [96–98]

96 [94–97]

0.82

0.700–0.93

0.01

SOFA* score = 0

83 (92.2%)

52 (70.3%)

Ref.

  

SOFA* score > = 1

7 (7.8%)

22 (29.7%)

5.02

2.09–13.45

0.001

Urine output (ml/h)

69.7 [42.2–125.5]

76.6 [42.9–113.3]

1.00

0.10–1.00

0.81

Creatinine (μmol/L)

78.9 (± 16.4)

90.9 (± 48.4)

1.01

1.00–1.03

0.04

Platelets (× 109/L)

283.6 (± 81.7)

282.8 (± 97.4)

1.00

1.00–1.00

0.96

Potassium (mEq/L) (n = 94)

3.6 (± 0.4)

3.7 (± 0.6)

1.59

0.72–3.75

0.27

White blood count (× 109/L) (n = 95)

9.6 [7.1–11.0]

10.2 [8.4–13.0]

1.15

1.02–1.34

0.04

  1. *Sequential organ failure score [20]. Descriptive statistic describe number of patients with SOFA score = 0 (reference) or > = 1