Characteristics | Viral meningitis N=19 (%) | Bacterial meningitis N=73 (%) | Tubercular meningitis N=13 (%) | P value |
---|---|---|---|---|
Age, median (p25-p75) | 31 (22–51) | 50 (32–60) | 50 (30–69) | 0.048 |
Male sex | 12 (63.2) | 55 (75.3) | 7 (53.9) | 0.218 |
Place of residence, rural | 7 (36.9) | 50 (68.5) | 10 (76.9) | 0.022 |
Exposure to animal, pig | 0 (0.0) | 7 (9.6) | 0 (0.0) | 0.379 |
Immunocompromised statea | 1 (5.3) | 10 (13.7) | 4 (30.8) | 0.146 |
Duration of fever at admission, ≥7 days | 6 (31.6) | 26 (35.6) | 7 (53.9) | 0.391 |
Headache | 16 (84.2) | 64 (87.7) | 11 (84.6) | 0.738 |
History of loss of consciousness | 11 (57.9) | 39 (53.4) | 9 (69.2) | 0.561 |
Neck stiffness | 6 (31.6) | 41(56.2) | 6 (46.2) | 0.153 |
Glasgow Coma Scale (n=102) | ||||
 8 to 14 | 10 (55.6) | 28 (39.4) | 8 (61.5) | 0.405 |
 <8 | 0 (0.0) | 6 (8.5) | 0 (0.0) |  |
Abnormal CT/MRI brain (n=62) | 9 (75.0) | 22 (56.4) | 4 (36.4) | 0.201 |
HIV positive | 1 (5.3) | 1 (1.4) | 2 (15.4) | 0.049 |
Lab findings | ||||
 White blood cells (109/L), median | 13.0 | 13.8 | 7.8 | 0.038 |
 Neutrophil count (109/L), median | 8.8 | 11.6 | 6.8 | 0.035 |
 Raised liver enzymes (AST>40 or ALT>35 U/L) (n=101) | 9 (47.4) | 43 (62.3) | 5 (38.5) | 0.191 |
 Raised blood urea (>7.1 mmol/L) (n=103) | 2 (10.5) | 16 (22.5) | 5 (38.5) | 0.181 |
 Raised CRP (≥1 mg/dL) (n=95) | 7 (43.8) | 50 (74.6) | 7 (58.3) | 0.047 |
 Raised procalcitonin (≥0.5 ng/mL) (n=38) | 3 (33.3) | 16 (57.1) | 0 (0.0) | 0.269 |
CSF analysis | ||||
 White blood cells (/μL), median | 70 | 525 | 250 | 0.002 |
 Neutrophil count (/μL), median | 33 | 297 | 175 | 0.003 |
 Protein (g/L), median | 0.8 | 2.1 | 1.7 | 0.001 |
 CSF/blood glucose ratio, median | 60.4 | 26.1 | 36.1 | 0.001 |
 ADA (IU/L), median (n=103) | 3.2 | 14.3 | 13.0 | 0.001 |
Outcome | ||||
 Complete recovery | 6 (31.6) | 16 (21.9) | 0 (0.0) | 0.001 |
 Referred to another hospital | 4 (21.0) | 16 (21.9) | 11 (84.6) |  |
 Incomplete recovery | 8 (42.1) | 30 (41.1) | 1 (7.7) |  |
 Not recovered-discharged to home | 1 (5.3) | 11 (15.0) | 1 (7.7) |  |
 Death at hospital | 0 (0.0) | 0 (0.0) | 0 (0.0) |  |