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Table 3 In vivo antioxidant properties of the aqueous and ethanolic extracts during P. berghei ANKA infection

From: Antioxidant and antimalarial properties of Sophora exigua Craib. root extract in Plasmodium berghei-infected mice

Group

MDA level (nmol/mg)

SOD inhibition (%)

Uninfected group

6.55 ± 1.11a

75.05 ± 3.53a

Infected untreated group

18.38 ± 1.34

57.89 ± 1.05

Artesunate 6 mg/kg

7.42 ± 1.61a

73.07 ± 0.02a

Ethanolic extract 200 mg/kg

8.58 ± 0.90a

61.60 ± 3.92

Ethanolic extract 400 mg/kg

8.41 ± 0.70a

64.82 ± 3.00a

Ethanolic extract 600 mg/kg

7.36 ± 0.84a

67.12 ± 2.34a

Aqueous extract 200 mg/kg

16.65 ± 1.86

59.86 ± 0.61

Aqueous extract 400 mg/kg

10.27 ± 0.67a

63.79 ± 1.74a

Aqueous extract 600 mg/kg

8.95 ± 0.75a

64.82 ± 3.00a

  1. Data are presented as the mean ± SD (n = 5 per group)
  2. Data were analyzed by one-way ANOVA, followed by post hoc Tukey’s multiple comparison test
  3. ap < 0.05, significantly different compared to the infected untreated group