Skip to main content

Table 2 Comparison of baseline characteristics among survivors and nonsurvivors

From: Hyperferritinemia in children hospitalized with scrub typhus

 

N

Total (n = 72)

Survivors (n = 60)

Nonsurvivors (n = 12)

P value

Parameter

 Age, months

72

60 (36, 96)

60 (30, 98)

36 (31, 105)

0.60

 Boys, n (%)

72

45 (62.5)

41 (68.3)

4 (33.3)

0.04

 PRISM III

72

8 (5, 12)

8 (5, 11)

12 (8.7, 17.5)

0.005

 Duration of illness, days

72

7 (5, 10)

7 (5, 9.5)

9 (5, 12)

0.38

Investigations

 Ferritin, μg/L

62

668 (420, 2714)

666 (382, 2653)

1806 (443, 4727)

0.53

  Normal (< 500), n (%)

 

17 (27.4)

15 (28.8)

2 (20)

0.42

  Mild (> 500–2000), n (%)

 

26 (41.9)

23 (44.2)

3 (30)

  Moderate (> 2000–10,000), n (%)

 

13 (21)

10 (19.2)

3 (30)

  Severe (> 10,000), n (%)

 

6 (9.7)

4 (7.8)

2 (20)

 Hemoglobin, g/dl

72

8.7 (7.4, 10.2)

8.6 (7.5, 10.5)

8.1 (6.8, 10.1)

0.48

 Total leukocyte count cells/mm3

72

14,000 (9820, 18,000)

14,090 (10,200, 17,500)

12465 (7020, 21,080)

0.39

 Platelet count cells/mm3

72

18,000 (44,000, 80,000)

19,000 (48,000, 80,000)

31000 (11,500, 100,000)

0.39

 Albumin, g/dl

58

2.2 (2.1, 2.6)

2.3 (2.1, 2.6)

2.1 (1.9, 2.2)

0.05

 Severe hypoalbuminemia (< 2.5 g/dl), n (%)

58

39 (54.2)

30 (50)

9 (75)

0.14

 Lactate, mmol/L

72

1.6 (1.1, 2.6)

1.6 (1, 1.8)

3.0 (1.85, 9.8)

0.04

Organ dysfunction

 Hematological dysfunction, n (%)

72

68 (94.4)

56 (93.3)

12 (100)

0.60

 Respiratory failure, n (%)

72

40 (55.5)

28 (46.6)

12 (100)

0.001

  ARDS, n (%)

72

23 (31.9)

13 (21.7)

10 (83.3)

< 0.0001

  Mechanical ventilation, n (%)

72

34 (47.2)

22 (36.7)

12 (100)

0.0001

 Shock, n (%)

72

20 (28.2)

12 (20.3)

8 (66.7)

0.003

  VIS on day 1

72

0 (0, 10)

0 (0,0)

10 (0,30)

0.0001

 AKI, n (%)

72

15 (20.8)

10 (16.7)

5 (41.7)

0.02

  RRT, n (%)

72

5 (6.9)

2 (3.3)

3 (25)

0.03

 CNS dysfunction, n (%)

72

10 (13.9)

6 (10)

4 (33.3)

0.05

 Coagulopathy (INR > 1.5), n (%)

56

12 (21.4)

10 (21.3)

2 (22.2)

1.0

 PELOD-2 score

     

  Day 1

72

3 (2, 7)

2 (2, 5)

7 (7, 9)

< 0.0001

  Day 2

67

2 (1, 5)

2 (1, 5)

6 (4, 7)

0.001

  Day 3

64

2 (1, 5)

2 (1, 4)

4 (1, 6)

0.32

  1. All values expressed as median (IQR)
  2. PRISM Pediatric Risk of Mortality, PELOD Pediatric Logistic Organ Dysfunction, ARDS Acute Respiratory distress syndrome, VIS vasoactive inotrope score, AKI acute kidney injury, RRT renal replacement therapy