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Table 4 Multivariable Cox regression analysis of predictors of LTFU among HIV-positive adult subjects on ART at Debre Markos Referral Hospital, North West Ethiopia, from January 30, 2008, to January 26, 2018

From: Incidence and predictors of loss to follow-up among HIV-positive adults in northwest Ethiopia: a retrospective cohort study

Variables

Last status

CHR (95% CI)

AHR (95% CI)

p value

Event

Censored

Sex

 Male

40

162

1.0

1.0

 

 Female

44

238

0.81 (0.53,1.23)

0.88 (0.54, 1.42)

0.58

ART regimen

 1a

8

56

1.0

1.0

 

 1b

13

48

1.6 (0.7, 3.9)

1.6 (0.6, 3.9)

0.37

 1c

14

66

1.99 (0.83, 4.8)

2.79 (1.07, 7.23)

0.32

 1d

9

31

2.4 (0.94, 6.4)

3.14 (1.13, 8.08)

0.19

 1e

40

199

6.7 (3.14, 14.7)

9.3 (3.75 , 23.8)

0.10

History of ART adherence

 

 Poor

23

77

1.0

1.0

 

 Good

61

323

0.5(0.3, 0.8)

1.2(0.3, 0.9)

0.20

WHO clinical stage

 Stage I

11

106

1.0

1.0

 

 Stage II

8

66

0.7 (0.29, 0.1.81)

1.09 (0.42, 2.85)

0.45

 Stage III

48

172

1.44 (0.75, 2.78)

1.73 (0.87, 3.46)

0.20

 Stage IV

17

56

1.8 (0.83, 3.8)

2.75 (1.23, 6.16)

0.01

Residence

 Urban

55

217

1.0

1.0

 

 Rural

29

183

0.5 (0.33, 0.8)

0.6 (0.37, 0.99)

0.046

Phone

 Yes

68

352

1.0

1.0

 

 No

16

48

1.5 (0.87, 2.6)

1.9 (1.14, 3.4)

0.04

Age categories

 15–24

13

40

1.0

1.0

 

 25–34

41

169

0.44 (.22, 0.88)

0.67 (0.35, 1.29)

0.20

 35–44

22

127

0.4 (0.22, 0.86)

0.32 (0.15, 0.67)

0.20

 ≥ 45

8

64

0.4 (0.17, 0.99)

0.33 (0.13, 0.83)

0.19

Baseline CD4 Count

 ≤ 50

11

46

1.0

1.0

 

 50–150

28

125

0.68 (0.34, 1.37)

0.76 (0.37, 1.57)

0.46

 150–200

12

53

0.58 (0.26, 1.33)

0.52 (0.21, 1.28)

0.16

 ≥ 200

33

176

1.14 (0.57, 2.27)

0.68 (0.32, 1.43)

0.31

History of TB infection

 No

56

273

1.0

1.0

 

 Yes

25

126

0.58 (0.36, 0.94

0.74 (0.43, 1.26)

0.27

History of ART regimen change

 No

54

273

1.0

1.0

 

 Yes

30

127

0.72 (0.46, 1.14)

1.59 (0.9, 2.8)

0.11