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Table 4 Multivariable Cox regression analysis of predictors of LTFU among HIV-positive adult subjects on ART at Debre Markos Referral Hospital, North West Ethiopia, from January 30, 2008, to January 26, 2018

From: Incidence and predictors of loss to follow-up among HIV-positive adults in northwest Ethiopia: a retrospective cohort study

Variables Last status CHR (95% CI) AHR (95% CI) p value
Event Censored
Sex
 Male 40 162 1.0 1.0  
 Female 44 238 0.81 (0.53,1.23) 0.88 (0.54, 1.42) 0.58
ART regimen
 1a 8 56 1.0 1.0  
 1b 13 48 1.6 (0.7, 3.9) 1.6 (0.6, 3.9) 0.37
 1c 14 66 1.99 (0.83, 4.8) 2.79 (1.07, 7.23) 0.32
 1d 9 31 2.4 (0.94, 6.4) 3.14 (1.13, 8.08) 0.19
 1e 40 199 6.7 (3.14, 14.7) 9.3 (3.75 , 23.8) 0.10
History of ART adherence  
 Poor 23 77 1.0 1.0  
 Good 61 323 0.5(0.3, 0.8) 1.2(0.3, 0.9) 0.20
WHO clinical stage
 Stage I 11 106 1.0 1.0  
 Stage II 8 66 0.7 (0.29, 0.1.81) 1.09 (0.42, 2.85) 0.45
 Stage III 48 172 1.44 (0.75, 2.78) 1.73 (0.87, 3.46) 0.20
 Stage IV 17 56 1.8 (0.83, 3.8) 2.75 (1.23, 6.16) 0.01
Residence
 Urban 55 217 1.0 1.0  
 Rural 29 183 0.5 (0.33, 0.8) 0.6 (0.37, 0.99) 0.046
Phone
 Yes 68 352 1.0 1.0  
 No 16 48 1.5 (0.87, 2.6) 1.9 (1.14, 3.4) 0.04
Age categories
 15–24 13 40 1.0 1.0  
 25–34 41 169 0.44 (.22, 0.88) 0.67 (0.35, 1.29) 0.20
 35–44 22 127 0.4 (0.22, 0.86) 0.32 (0.15, 0.67) 0.20
 ≥ 45 8 64 0.4 (0.17, 0.99) 0.33 (0.13, 0.83) 0.19
Baseline CD4 Count
 ≤ 50 11 46 1.0 1.0  
 50–150 28 125 0.68 (0.34, 1.37) 0.76 (0.37, 1.57) 0.46
 150–200 12 53 0.58 (0.26, 1.33) 0.52 (0.21, 1.28) 0.16
 ≥ 200 33 176 1.14 (0.57, 2.27) 0.68 (0.32, 1.43) 0.31
History of TB infection
 No 56 273 1.0 1.0  
 Yes 25 126 0.58 (0.36, 0.94 0.74 (0.43, 1.26) 0.27
History of ART regimen change
 No 54 273 1.0 1.0  
 Yes 30 127 0.72 (0.46, 1.14) 1.59 (0.9, 2.8) 0.11