Ethnobotany, ethnopharmacology, and phytochemistry of traditional medicinal plants used in the management of symptoms of tuberculosis in East Africa: a systematic review

Table 3 Isolation and characterization studies on medicinal plants used for management of TB in East Africa

Plant	Pure compounds with antitubercular activity	Chemical class	MIC of pure compounds (μg/ml)	Author(s)
Zanthoxylum leprieurii	2-hydroxy-1, 3-dimethoxy-10-methyl-9-acridone (1), 1-hydroxy-3-methoxy-10-methyl-9-acridone (2), 3-hydroxy-1, 5, 6-trimethoxy-9-acridone (3)	Acridone alkaloids	1.5 (1), 0.2 (2), 0.4 (3); tested against H37Rv	[5]
Warburgia ugandensis Sprague	Muzigadial (4), muzigadiolide (5), linoleic acid (6)	Sesquiterpenes	64 (4), 128 (5), 16 (6); tested against M. smegmatis	[58, 85]
Tetradenia riparia	15- sandaracopimaradiene-7α, 18-dio1 (7)	Diterpenediol	25–100	[37]

MIC minimum inhibitory concentration. No toxicity studies of the pure compounds were conducted.

ISSN: 1349-4147