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Table 4 Determinants of neonatal mortality that admitted to neonatal intensive care unit of Dessie Referral Hospital, Northeast Ethiopia, 2017/2018 (n = 384)

From: Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study

Variables

Cases (n = 126) (%)

Controls (n = 258) (%)

COR (95% CI)

AOR (95% CI)

Hypertensive disorders of pregnancy

 Yes

14 (11.1)

6 (2.3)

5.22 (1.95–13.96)

4.57 (1.45–14.43)**

 No

112 (88.9)

252 (97.3)

1

1

Maternal hemorrhage (antepartum hemorrhage)

 Yes

12 (9.5)

7 (2.7)

3.75 (1.44–9.79)

3.28 (0.86–12.46)

 No

114 (90.5)

251 (97.3)

1

1

Duration of rupture of membrane

  

 ≥ 12 h

36 (28.6)

43 (16.7)

1.92 (1.15–3.22)

2.04 (1.13–3.68)*

 < 12 h

82 (65.1)

189 (73.3)

1

1

Gestational age in completed weeks

 < 37

44 (34.9)

63 (24.4)

1.66 (1.04–2.64)

0.43 (0.17–1.10)

 ≥ 37

82 (65.1)

195 (75.6)

1

1

Weight at admission in grams

 700–1499

24 (19.0)

14 (5.4)

4.99 (2.42-10.29)

7.00 (2.10-23.35)**

 1500–2499

43 (34.1)

72 (27.9)

1.74 (1.07-2.81)

2.12 (1.10-4.20)*

 ≥ 2500

59 (46.8)

172 (66.7)

1

1

Perinatal asphyxia

 Yes

40 (31.8)

37 (14.3)

2.77 (1.66–4.63)

2.27 (1.18–4.39)*

 No

86 (68.3)

221 (85.7)

1

1

Meconium aspiration syndrome

 Yes

24 (19.1)

23 (8.9)

2.40 (1.29–4.54)

2.35 (1.12–4.97)*

 No

102 (81.0)

235 (91.1)

 

1

Congenital anomalies

 Yes

12 (9.5)

14 (5.4)

1.83 (0.82–4.09)

1.89 (0.67–5.34)

 No

114 (90.5)

244 (94.6)

1

1

Respiratory distress syndrome

 Yes

16 (12.7)

8 (3.1)

4.54 (1.88–10.93)

3.61 (1.10–12.04)*

 No

110 (87.3)

250 (96.9)

1

1

Infection (sepsis, meningitis, pneumonia)

 Yes

78 (61.9)

109 (42.3)

2.22 (1.43–3.43)

2.25 (1.34–3.78)**

 No

48 (38.1)

149 (57.8)

1

1

Hypoglycemia

 Yes

10 (7.9)

7 (2.7)

3.09 (1.14–8.32)

2.61 (0.77–8.79)

 No

116 (92.1)

251 (97.3)

1

1

  1. *Significant at p < 0.05
  2. **Significant at p < 0.01