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Table 3 Poisson regression with multilevel analysis (health facility as cluster variable) of the determinants of mortality rates among PLHIV in Northern Tanzania (N = 82,925)

From: Effect of tuberculosis infection on mortality of HIV-infected patients in Northern Tanzania

Characteristics

Survival status Event (death) censored

Crude rate ratio (95%CI)

Adjusted rate ratio (95%CI) adjusting only for clusters

ARR (95% CI) adjusting for other factors and for clusters *

Age

 15–24

258

7812

1

1

1

 25–34

853

22,795

1.03 (0.90–1.19)

1.06 (0.92–1.22)

1.21 (0.97–1.51)

 35–44

1600

27,407

1.14 (1.00–1.31)

1.17 (1.03–1.34)

1.30 (1.05–1.61)

 55–55

1147

15,759

1.21 (1.05–1.39)

1.24 (1.08–1.43)

1.23 (0.98–1.54)

Above 55

899

7520

1.90 (1.64–2.19)

1.92 (1.66–2.21)

1.88 (1.50–2.37)

Sex

 Male

1906

23,712

1

1

1

 Female

2851

60,465

0.57 (0.54–0.60)

0.57 (0.54–0.60)

0.62 (0.56–0.69)

HIV WHO stage

 Stage 1

482

21,756

1

1

1

 Stage 2

940

18,974

1.45 (1.30–1.61)

1.51 (1.36–1.68)

1.38 (1.13–1.69)

 Stage 3

2091

30,257

1.74 (1.59–1.92)

1.90 (1.73–2.09)

1.58 (1.32–1.90)

 Stage 4

1159

10,801

2.70 (2.43–2.99)

3.01 (2.75–3.39)

2.08 (1.71–2.54)

Region

 Arusha

517

13,799

1

1

1

 Kilimanjaro

1293

28,231

0.73 (0.66–0.80)

0.76 (0.69–0.85)

0.88 (0.74–1.03)

 Tanga

2946

42,148

0.93 (0.85–1.02)

0.95 (0.87–1.04)

0.78 (0.69–0.91)

Functional status

 Bedridden

503

3696

1

1

1

 Ambulatory

78

512

1.90 (1.51–2.39)

1.96 (1.56–2.47)

3.59 (2.39–5.39)

 Working

4152

79,342

0.38 (0.34–0.41)

0.38 (0.35–0.42)

0.56 (0.47–0.68)

TB status

 No TB

4085

79,403

1

1

1

 TB Co-infection

671

4775

2.23 (2.06–2.41)

2.25 (2.08–2.44)

1.4 (1.24–1.67)

Nutritional status **

 Ok

3237

60,389

1

1

1

 Moderate

511

4332

2.11 (1.93–2.31)

2.06 (1.90–2.28)

1.61 (1.39–1.85)

 Severe

53

342

4.06 (3.15–5.24)

4.15 (3.21–5.36)

1.90 (1.24–2.90)

Body weight***

 Below 40 kg

691

7302

1

1

1

 40–60 kg

3014

46,801

0.77 (0.72–0.83)

0.77 (0.72–0.83)

0.50 (0.43–0.58)

 Above 60 kg

790

24,780

0.39 (0.35–0.42)

0.39 (0.36–0.43)

0.26 (0.22–0.31)

CD4 count****

Below 350

1479

16,356

1

1

1

 350–500

157

4599

0.41 (0.35–0.48)

0.42 (0.36–0.49)

0.48 (0.39–0.58)

 above 500

100

5322

0.31 (0.25–0.37)

0.31 (0.26–0.38)

0.40 (0.32–0.51)

  1. *Adjusted for age, sex, region, WHO stage, functional status, TB status (N = 77,369)
  2. **Adjusted for age, sex, region, WHO stage, functional status, TB status (N = 65,063)
  3. ***Adjusted for age, sex, region, WHO stage, functional status, TB status (N = 71,813)
  4. ****Adjusted for age, sex, bodyweight, region, WHO stage, functional status, TB status (N = 26,277)