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Table 1 Pre and post-treatment prevalence (%) and intensity (EPG) of S. mansoni infection among Sanja General Elementary school children, Northwest Ethiopia, 2017

From: Praziquantel is an effective drug for the treatment of Schistosoma Mansoni infection among school-aged children in Northwest Ethiopia

Variables

Pre-treatment

Post-treatment

% positive (no. pos./no exam)

GMEPG

% positive (no. pos./no exam)

GMEPG

% reduction in prevalence

% reduction in GMEPG

Age groups

 6–9 years

80.9 (85/105)

421.8

13.8 (11/80)

77.79

87.1

81.4

 10–14 years

85.5 (118/138)

303.34

11.6 (11/95)

74.3

90.7

70.8

 ≥ 15 years

50 (1/2)

360

100 (1)

120

0

66.7

χ2 (p)

2.89 (0.193)

 

4.59 (0.17)

17.3 (0.33)

  

Sex

 Male

83.1 (138/166)

415.06

12.1(14/116)

102

89.6

75.4

 Female

83.5 (66/79)

284.03

15 (9/60)

51

86.4

80.1

χ2 (p)

0.007 (0.936)

 

5.92 (0.67)

5.92 (0.67)

  
  1. χ2 chi-square, p p value, no number of, GMEPG geometric mean egg per gram
  2. Four weeks post-treatment, stool samples were collected from 176 children who had tested positive and been treated at the baseline survey (Table 2). Of these, 23 were still positive for S. mansoni ova; 54.5% and 45.5 % had light and moderate intensity of infections, respectively. The lowest prevalence after treatment was 11.6% among 10–14 years old children. Both prevalence and intensity of infection were not significantly associated with age and sex of study participants during pre-treatment as well as post-treatment (Table 3).