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Table 3 The effect of ivermectin with diminazene aceturate, atovaquone, and clofazimine against Babesia and Theileria parasites in vitro

From: Evaluation of the inhibitory effect of ivermectin on the growth of Babesia and Theileria parasites in vitro and in vivo

Drug combinations

 

Parasites

B. bovis

B. bigemina

B. divergens

B. caballi

T. equi

IVM + DA

CI values

1.11051

0.40539

0.01779

0.14328

1.10124

Degree of association

Additive

Synergistic

Synergistic

Synergistic

Additive

IVM + AQ

CI values

1.04737

0.82283

1.04901

1.07398

1.05367

Degree of association

Additive

Synergistic

Additive

Additive

Additive

IVM + CF

CI values

0.92317

1.01390

1.01372

1.10847

0.99644

Degree of association

Additive

Additive

Additive

Additive

Additive

  1. CI combination index, AQ atovaquone, CF clofazimine, DA diminazene aceturate