Fig. 4
From: Pharmacokinetic analysis of new synthetic antimalarial N-251
Effect of multiple oral dosing on plasma concentration-time profile of N-251. A dose of 68 mg/kg of N-251 was orally administered every 8 h in normal-fed mice. Results were expressed as mean with the bar showing the SD value. The solid line was the simulation line calculated utilizing the equation shown in the “Methods” section as obtained in the fitting study for plasma concentration profile after a single oral administration