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Table 1 Comparison of nitrate reductase assay results with conventional proportion method

From: Evaluation of nitrate reductase assay in 7H11 agar for diagnosis of multi-drug-resistant tuberculosis in eastern Nepal

Drugs

Conventional PM

Nitrate reductase assay

Resistant

Sensitive

Sensitivity (95% CI)

Specificity (95% CI)

PPV (%)

NPV (%)

Agreement (%)

Kappa

Rifampicin

Resistant

6

1

85.7 (42–99)

100 (90–100)

100

97.8

98.1

0.912

Sensitive

0

45

Isoniazid

Resistant

7

1

87.5 (46.6–99.3)

100 (90–100)

100

97.7

98.1

0.922

Sensitive

0

44