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Table 4 Efficacy of praziquantel against S. haematobium on day 42 post-treatment with respect to initial infection intensity in the Ikata-Likoko area of southwest Cameroon

From: Efficacy and safety of praziquantel against Schistosoma haematobium in the Ikata-Likoko area of southwest Cameroon

Characteristic

Category

Prevalence day 0 (n) (N = 174)

Prevalence day 42 (n) (N = 130)

Mean egg load on day 0 (range)

Mean egg load on day 42 (range)

Z test

P value

ERR (%)

Infection intensity

Light ≤ 50 eggs/10 mL

100 (155)

20.8 (27)

15.53

(1–50)

6.15(1–35)

5.33

< 0.001

60.4

Heavy > 50 eggs/10 mL

100 (19)

1.6 (2)

153.58

(56–400)

6.00(4–8)

2.03

0.04

96.1

Level of significance

V = 0.3, P < 0.0001

U = 4.32, P = 0.13

  

Overall

 

100 (174)

22.3(29)

31 (1–400)

6 (1–35)

5.73

< 0.001

80.3