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Table 4 Parasite ligands, host receptors, and clinical consequences [6163]

From: Molecular basis of human cerebral malaria development

Receptor PfEMP1 domain Clinically significant
CD36 CIDR1α Uncomplicated/severe malaria
ICAM-1 DBL2/β type Cerebral malaria
CSA DBL3/γ type, CIDR1α Placental infection and other forms
HS DBL1α RBC rosette formation
CR1 DBL1α Rosette/immune complex formation/parasite invasion
CD31/PECAM CIDR1α, DBL2/δ type Virulence-associated endothelial receptor