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Table 3 Genetic variants associated with CM in Asians

From: Molecular basis of human cerebral malaria development

No. Gene SNP/region P value Odds ratio Population Ref.
1 ABCA1 −477 and −320/promoter <0.0001 5.5 Indian [51]
2 CR1 intron 27, exon 22 0.0003 3.03 Indian [52]
rs9429942/promoter 0.0009 0.25 Thai [53]
3 TNF-α −308 0.04 ND Gambia [54]
−238, −308, −857, −863, and −1031/promoter haplotype <0.001 34.5 Myanmar [55]
4 TIM1 rs7702919, rs41297577, rs41297579/promoter haplotype 0.0009 0.41 Thai [56]
5 ICAM-1 K29M/N-terminal domain >0.05 ND Thai [57]
K29M/N-terminal domain 0.0042 1.39 Kenyan [58]
6 HO-1 Promoter >0.05   Thai, Karen Myanmar [59]
Promoter <0.008 3.14 Myanmar [60]
7 PECAM-1 125 V/V and 563 N/N/coding region <0.01 2.92 Thai [61]
8 CD36 539delAC 0.04 ND Thai [62]
−14/promoter 0.016 0.62 Thai [63]
−53/promoter 0.05 0.68 Thai [63]