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Table 2 Selective index of compounds tested for anti-Leishmania activity

From: In vitro anti-Leishmania activity of tetracyclic iridoids from Morinda lucida, benth

  IC50 (μM), 48 h SI
ML-2-2 ML-2-3 ML-F52 ML-2-2 ML-2-3 ML-F52
IC50 of anti-leishmanial activity 4.24 >50 3.38    
Normal skin fibroblasts NBIRGB 7.11 >50 4.74 1.67 >0.14 1.4
Normal lung fibroblasts HF-19 14.24 >50 10.94 3.36 >0.28 3.23
Normal lung Hs-888Lu 9.29 >50 8.89 2.19 >0.19 2.63
Normal liver Chang Liver 9.34 >50 18.13 2.20 >0.19 5.36