Table 2 Selective index of compounds tested for anti-Leishmania activity
From: In vitro anti-Leishmania activity of tetracyclic iridoids from Morinda lucida, benth
|  | IC50 (μM), 48 h | SI | |||||
|---|---|---|---|---|---|---|---|
ML-2-2 | ML-2-3 | ML-F52 | ML-2-2 | ML-2-3 | ML-F52 | ||
IC50 of anti-leishmanial activity | 4.24 | >50 | 3.38 | Â | Â | Â | |
Normal skin fibroblasts | NBIRGB | 7.11 | >50 | 4.74 | 1.67 | >0.14 | 1.4 |
Normal lung fibroblasts | HF-19 | 14.24 | >50 | 10.94 | 3.36 | >0.28 | 3.23 |
Normal lung | Hs-888Lu | 9.29 | >50 | 8.89 | 2.19 | >0.19 | 2.63 |
Normal liver | Chang Liver | 9.34 | >50 | 18.13 | 2.20 | >0.19 | 5.36 |