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Table 1 Michaelis constant (K m ) approximation

From: Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease

  Michaelis-Menten model Substrate inhibition model
Max substrate conc. 1000 μM 500 μM 1000 μM 500 μM
K m in μM (95 % CI) 51.23 (36.80 to 65.66) 76.24 (58.24 to 94.24) 135.0 (99.52 to 170.4) 171.7 (88.73 to 254.6)
Adjusted R square 0.8965 0.9638 0.9687 0.9796
  1. Estimates of K m derived from varied nonlinear regression models and substrate maximal concentrations at initial velocity conditions were presented