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Table 1 Supplements and chemicals selected for in vitro screening of T. b. brucei

From: Anti-trypanosome effects of nutritional supplements and vitamin D3: in vitro and in vivo efficacy against Trypanosoma brucei brucei

Chemical name

Structural formula

Molecular weight (g/mol)

Function

Polyphenon-60

290.3

Mainly anti-oxidative effects and also anti-cancer, anti-inflammatory [31]

Catechin hydrate

290.3

Able to impart thermal stability to collagen [32]

Epigallocatechin gallate

458.4

Modulates cognitive function and brain activity [33]

5-Aminolevrinic acid

167.6

Helps in heme synthesis, heme protein design [34]

Coenzyme Q10

863.34

Act as an anti-oxidant, needed for basic cellular function [35]

Vitamin C

198.11

An anti-oxidant, required for collagen synthesis and biosynthesis of certain hormones [36]

Vitamin D3

384.64

An immunomodulator, supports the brain and nervous system [37]

Vitamin E

430.71

Essential for neurological function [38]

Curcumin

368.38

Exhibits anti-cancer, chemo- preventive, chemo- and radio-sensitization properties [39]