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Table 1 Supplements and chemicals selected for in vitro screening of T. b. brucei

From: Anti-trypanosome effects of nutritional supplements and vitamin D3: in vitro and in vivo efficacy against Trypanosoma brucei brucei

Chemical name Structural formula Molecular weight (g/mol) Function
Polyphenon-60 290.3 Mainly anti-oxidative effects and also anti-cancer, anti-inflammatory [31]
Catechin hydrate 290.3 Able to impart thermal stability to collagen [32]
Epigallocatechin gallate 458.4 Modulates cognitive function and brain activity [33]
5-Aminolevrinic acid 167.6 Helps in heme synthesis, heme protein design [34]
Coenzyme Q10 863.34 Act as an anti-oxidant, needed for basic cellular function [35]
Vitamin C 198.11 An anti-oxidant, required for collagen synthesis and biosynthesis of certain hormones [36]
Vitamin D3 384.64 An immunomodulator, supports the brain and nervous system [37]
Vitamin E 430.71 Essential for neurological function [38]
Curcumin 368.38 Exhibits anti-cancer, chemo- preventive, chemo- and radio-sensitization properties [39]