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Fig. 1 | Tropical Medicine and Health

Fig. 1

From: Anti-trypanosome effects of nutritional supplements and vitamin D3: in vitro and in vivo efficacy against Trypanosoma brucei brucei

Fig. 1

Reductions of parasitemia level of supplement-treated mice. a Parasitemia levels in mice infected with T. b. brucei GUTat 3.1 and treated with 500 ng/kg vitamin D3 and 250 ng/kg vitaminD3. Solid triangles (▲) with a dotted line show parasitemia of 500 ng/kg vitamin D3-treated group. Solid circles () with a solid line, closed squares (■) with broken line, and solid diamonds () with a solid line show 250 ng/kg vitamin D3-treated group, non-treated control group, and suramin-treated group, respectively. b Parasitemia levels in mice infected with T. b. brucei and treated with 50 mg/kg polyphenon-60. Solid circles () with solid line show survival rates of polyphenon-60-treated group, and solid squares (■) with a broken line show those of non-treated control group. Vitamin D3-inhibited level of parasitemia was significantly lower than that of control-infected mice (P < 0.05). Polyphenon-60-treated group also showed inhibition, but it was not statistically significant (P = 0.056)

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